By approximately what percentage does low tubular flow increase urea reabsorption?

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Multiple Choice

By approximately what percentage does low tubular flow increase urea reabsorption?

Explanation:
Low tubular flow lets urea stay in contact with the tubular epithelium longer and reduces its washout, so more urea can diffuse from the lumen into the medullary interstitium via the UT-A1/UT-A3 transporters in the inner medullary collecting ducts. This passive diffusion and recycling of urea back into the medullary interstitium increases overall urea reabsorption by about sixty percent. This greater reabsorption helps raise medullary osmolality and supports the kidney’s ability to concentrate urine when water is scarce.

Low tubular flow lets urea stay in contact with the tubular epithelium longer and reduces its washout, so more urea can diffuse from the lumen into the medullary interstitium via the UT-A1/UT-A3 transporters in the inner medullary collecting ducts. This passive diffusion and recycling of urea back into the medullary interstitium increases overall urea reabsorption by about sixty percent. This greater reabsorption helps raise medullary osmolality and supports the kidney’s ability to concentrate urine when water is scarce.

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